Postdoctoral scholarship (2 years) within cancer research in C. elegans
Medicinska fakulteten, Institutionen för Diagnostik och intervention
Umeå University is one of Sweden’s largest higher education institutions with over 37,000 students and about 4,700 employees. The University offers a diversity of high-quality education and world-leading research in several fields. Notably, the groundbreaking discovery of the CRISPR-Cas9 gene-editing tool, which was awarded the Nobel Prize in Chemistry, was made here. At Umeå University, everything is close. Our cohesive campuses make it easy to meet, work together and exchange knowledge, which promotes a dynamic and open culture.
The ongoing societal transformation and large green investments in northern Sweden create enormous opportunities and complex challenges. For Umeå University, conducting research about – and in the middle of – a society in transition is key. We also take pride in delivering education to enable regions to expand quickly and sustainably. In fact, the future is made here.
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The Faculty of Medicine, which consists of 12 departments, is responsible for biomedical research and courses in the field of nursing and health care and has an extensive research and graduate education in more than 80 subjects.
The Department of Diagnostics and Intervention is offering a postdoctoral scholarship within the project “Genetic- and chemical screens in C. elegans to identify suppressors of oncogenes in the MAPK-pathway”. The scholarship is full-time for two years with access 01-05-2025 or by agreement.
Departmental specific information
At the Department of Diagnostics and Intervention, Umeå University, we conduct research and teaching across nine different subject areas in close collaboration with healthcare in the four Norrland regions. Our internationally recognized research environments enable innovation and cross-border collaboration.
The Department of Diagnostics and Intervention is now seeking a postdoctoral researcher to conduct postdoctorial studies within a project focused on the MAPK signaling pathway in cancer, using both Caenorhabditis elegans and cell line models. The project will be conducted in state-of-the-art labs located at the Translational Research Center (https://www.umu.se/en/research/groups/trc---translational-research-centre/) in collaboration with the Chemical Biology Consortium Sweden. In our laboratory, researchers from diverse disciplines collaborate and share both ideas and infrastructure. Here, you can interact with colleagues in seminar series, journal clubs and in the openminded lab environment.
Project description
An appointment as a postdoctoral fellow aims to provide an early opportunity to develop research independence and to create the right conditions for acquiring further qualifications.
The successful candidate will play a central role in a groundbreaking project aimed at developing novel MAPK/ERK signaling inhibitors and identifying genetic suppressors of MAPK pathway oncogenes.
Within the positive and collaborative spirit in the lab, you will have great opportunities for intellectual development new merits.
The postdoctoral researcher will have the opportunity to:
- Develop elegans and human cell line models for MAPK-targeted drug discovery and genetic screens.
- Carry out high-throughput screens to discover new drug candidates and gene targets.
- Validate hits using proteomic and genetic approaches.
Qualifications
To qualify as a postdoctoral scholarship holder, the postdoctoral fellow is required to have completed a doctoral degree or a foreign degree deemed equivalent to a doctoral degree. This qualification requirement must be fulfilled no later than at the time of the decision about scholarship recipient.
Priority should be given to candidates who completed their doctoral degree no later than three years prior. If there are special reasons, candidates who completed their doctoral degree before that may also be eligible. Special reasons include absence due to illness, parental leave, appointments of trust in trade union organizations, military service, or similar circumstances, or other forms of appointment/assignment relevant to the subject area.
Doctoral degree should be within in a relevant field and from a non-Swedish university.
Additional requirements are familiarity with genetic manipulation techniques and cell culture. Excellent communication skills in English, both written and spoken, are necessary. The applicant must fulfill the criteria for scholarship from the Kempe foundations and the criteria for post doc stipends at Umeå university.
Meriting criteria are experience with C. elegans, a strong background in cancer biology, along with experience in proteomics or chemical genetics. The ideal candidate will have strong organizational and administrative skills, and the ability collaborate in a multidisciplinary team.
Application
The application should be written in English, and attached documents should be in Word or PDF format. The application should be registered via Umeå University’s e-recruitment system Varbi and submitted by the deadline 31-03-2025.
Further information
Principal investigator Oskar Hemmingsson oskar.hemmingsson@umu.se
Staff scientist Ola Billing ola.billing@umu.se
Human Resource coordinator Marie Eriksson marie.s.eriksson@umu.se
We look forward to receiving your application!
| First day of employment | Enligt överenskommelse |
|---|---|
| Salary | Stipendium |
| Full-time equivalent | 100 |
| City | Umeå |
| County | Västerbottens län |
| Country | Sweden |
| Reference number | FS 2.1.6-424-25 |
| Published | 20.Feb.2025 |
| Last application date | 31.Mar.2025 11:59 PM CEST |